A
risk factor is anything that affects your chance of getting a disease,
such as breast cancer. But having a risk factor, or even many, does not
mean that you are sure to get the disease.
Certain breast cancer risk factors are related to personal
behaviors, such as diet and exercise. Other lifestyle-related risk
factors include decisions about having children and taking medicines
that contain hormones.
Drinking alcohol
Drinking alcohol
is clearly linked to an increased risk of breast cancer. The risk
increases with the amount of alcohol consumed. Compared with
non-drinkers, women who have 1 alcoholic drink a day have a very small
increase in risk. Those who have 2 to 3 drinks a day have about a 20%
higher risk compared to women who don’t drink alcohol.
Excessive alcohol consumption is known to increase the risk of other
cancers, too.
Being overweight or obese
Being overweight or obese
after menopause increases breast cancer risk. Before menopause your
ovaries make most of your estrogen, and fat tissue makes only a small
amount. After menopause (when the ovaries stop making estrogen), most of
a woman’s estrogen comes from fat tissue. Having more fat tissue after
menopause can raise estrogen levels and increase your chance of getting
breast cancer. Also, women who are overweight tend to have higher blood
insulin levels. Higher insulin levels have been linked to some cancers,
including breast cancer.
Still, the link between weight and breast cancer risk is complex.
For instance, risk appears to be increased for women who gained weight
as an adult, but may not be increased among those who have been
overweight since childhood.
Also, excess fat in the waist area may affect risk more than the
same amount of fat in the hips and thighs. Researchers believe that fat
cells in various parts of the body have subtle differences that may
explain this.
Weight might also have different effects on different types of
breast cancer. For example, some research suggests that being overweight
before menopause might increase your risk of triple-negative breast
cancer.
The American Cancer Society recommends you stay at a healthy weight
throughout your life and avoid excess weight gain by balancing your
food intake with physical activity.
Not being physically active
Evidence is growing that regular physical activity reduces breast
cancer risk, especially in women past menopause. The main question is
how much activity is needed. Some studies have found that even as little
as a couple of hours a week might be helpful
, although more seems to be better.
Exactly how physical activity might reduce breast cancer risk isn’t
clear, but it may be due to its effects on body weight, inflammation,
hormones, and energy balance.
The American Cancer Society recommends
that adults get at least 150 minutes of moderate intensity or 75
minutes of vigorous intensity activity each week (or a combination of
these), preferably spread throughout the week.
Not having children
Women who have not had children or who had their first child after
age 30 have a slightly higher breast cancer risk overall. Having many
pregnancies and becoming pregnant at an early age reduces breast cancer
risk. Still, the effect of pregnancy seems to be different for different
types of breast cancer. For a certain type of breast cancer known as
triple-negative, pregnancy seems to increase risk.
Not breastfeeding
Some studies suggest that breastfeeding may slightly lower breast
cancer risk, especially if it’s continued for 1½ to 2 years.
But this has been hard to study, especially in countries like the
United States, where breastfeeding for this long is uncommon.
The explanation for this possible effect may be that breastfeeding
reduces a woman’s total number of lifetime menstrual cycles (the same as
starting menstrual periods at a later age or going through early
menopause).
Birth control
Some birth control methods use hormones, which might increase breast cancer risk.
Oral contraceptives: Most studies have found that
women using oral contraceptives (birth control pills) have a slightly
higher risk of breast cancer than women who have never used them. Once
the pills are stopped, this risk seems to go back to normal over time.
Women who stopped using oral contraceptives more than 10 years ago do
not appear to have any increased breast cancer risk.
Birth control shot:
Depo-Provera
is an injectable form of progesterone that’s given once every 3 months
for birth control. Some studies have found that women currently using
birth-control shots seem to have an increase in breast cancer risk,
but it appears that there is no increased risk in women 5 years
after they stop getting the shots.
Birth control implants, intrauterine devices (IUDs), skin patches, vaginal rings:
These forms of birth control also use hormones, which in theory could
fuel breast cancer growth. Some studies have shown a link between use of
hormone-releasing IUDs and breast cancer risk,
but few studies have looked at the use of birth control implants,
patches, and rings and breast cancer risk.
When thinking about using hormonal birth control, women should
discuss their other risk factors for breast cancer with their health
care provider.
Hormone therapy after menopause
Hormone therapy
with estrogen (often combined with progesterone) has been used for many
years to help relieve symptoms of menopause and help prevent
osteoporosis (thinning of the bones). This treatment goes by many names,
such as
post-menopausal hormone therapy (PHT),
hormone replacement therapy (HRT), and
menopausal hormone therapy (MHT).
There are 2 main types of hormone therapy. For women who still have
a uterus (womb), doctors generally prescribe estrogen and progesterone
(known as
combined hormone therapy or HT). Progesterone is needed because estrogen alone can increase the risk of cancer of the uterus. For women who’ve had a hysterectomy (who no longer have a uterus), estrogen alone can be used. This is known as
estrogen replacement therapy (ERT) or just
estrogen therapy (ET).
Combined hormone therapy (HT): Use of combined
hormone therapy after menopause increases the risk of breast cancer. It
may also increase the chances of dying from breast cancer. This increase
in risk can be seen with as little as 2 years of use. Combined HT also
increases the likelihood that the cancer may be found at a more advanced
stage.
The increased risk from combined HT appears to apply only to
current and recent users. A woman’s breast cancer risk seems to return
to that of the general population within 5 years of stopping treatment.
Bioidentical hormone therapy: The word
bioidentical
is sometimes used to describe versions of estrogen and progesterone
with the same chemical structure as those found naturally in people. The
use of these hormones has been marketed as a safe way to treat the
symptoms of menopause. But because there aren’t many studies comparing
“bioidentical” or “natural” hormones to synthetic versions of hormones,
there’s no proof that they’re safer or more effective. More studies are
needed to know for sure. The use of these bioidentical hormones should
be considered to have the same health risks as any other type of hormone
therapy.
Estrogen therapy (ET): The use of estrogen alone
after menopause does not seem to increase the risk of breast cancer
much, if at all. But when used long term (for more than 15 years), ET
has been found to increase the risk of ovarian and breast cancer in some
studies.
At this time there aren't many strong reasons to use
post-menopausal hormone therapy (either combined HT or ET), other than
possibly for the short-term relief of menopausal symptoms. Along with
the increased risk of breast cancer, combined HT also appears to
increase the risk of heart disease, blood clots, and strokes. It does
lower the risk of colorectal cancer and osteoporosis, but this must be
weighed against the possible harms, especially since there are other
ways to prevent and treat osteoporosis, and screening can sometimes prevent colon cancer. ET does not seem to increase breast cancer risk, but it does increase the risk of stroke.
The decision to use HT should be made by a woman and her doctor
after weighing the possible risks and benefits (including the severity
of her menopausal symptoms), and considering her other risk factors for
heart disease, breast cancer, and osteoporosis. If they decide she
should try HT for symptoms of menopause, it’s usually best to use it at
the lowest dose that works for her and for as short a time as possible.
Breast implants
Silicone breast implants can cause scar tissue to form in the
breast. Implants make breast tissue harder to see on standard
mammograms, but additional x-ray pictures called
implant displacement views can be used to examine the breast tissue more completely.
Certain types of breast implants can be linked to a rare type of cancer called anaplastic large cell lymphoma (ALCL).
It' is sometimes referred to as breast implant-associated anaplastic
large cell lymphoma (BIA-ALCL). This lymphoma appears to happen more
often in implants with textured (rough) surfaces rather than smooth
surfaces. If ALCL does show up after an implant, it can show up as a
lump, a collection of fluid near the implant, pain, swelling or
asymmetry (uneven breasts). It usually responds well to treatmen
A
risk factor is anything that affects your chance of getting a disease,
such as breast cancer. But having a risk factor, or even many, does not
mean that you are sure to get the disease.
Certain breast cancer risk factors are related to personal
behaviors, such as diet and exercise. Other lifestyle-related risk
factors include decisions about having children and taking medicines
that contain hormones.
Drinking alcohol
Drinking alcohol
is clearly linked to an increased risk of breast cancer. The risk
increases with the amount of alcohol consumed. Compared with
non-drinkers, women who have 1 alcoholic drink a day have a very small
increase in risk. Those who have 2 to 3 drinks a day have about a 20%
higher risk compared to women who don’t drink alcohol.
Excessive alcohol consumption is known to increase the risk of other
cancers, too.
The American Cancer Society recommends that women who drink have no more than 1 drink a day.
Being overweight or obese
Being overweight or obese
after menopause increases breast cancer risk. Before menopause your
ovaries make most of your estrogen, and fat tissue makes only a small
amount. After menopause (when the ovaries stop making estrogen), most of
a woman’s estrogen comes from fat tissue. Having more fat tissue after
menopause can raise estrogen levels and increase your chance of getting
breast cancer. Also, women who are overweight tend to have higher blood
insulin levels. Higher insulin levels have been linked to some cancers,
including breast cancer.
Still, the link between weight and breast cancer risk is complex.
For instance, risk appears to be increased for women who gained weight
as an adult, but may not be increased among those who have been
overweight since childhood.
Also, excess fat in the waist area may affect risk more than the
same amount of fat in the hips and thighs. Researchers believe that fat
cells in various parts of the body have subtle differences that may
explain this.
Weight might also have different effects on different types of
breast cancer. For example, some research suggests that being overweight
before menopause might increase your risk of triple-negative breast
cancer.
The American Cancer Society recommends you stay at a healthy weight
throughout your life and avoid excess weight gain by balancing your
food intake with physical activity.
Not being physically active
Evidence is growing that regular physical activity reduces breast
cancer risk, especially in women past menopause. The main question is
how much activity is needed. Some studies have found that even as little
as a couple of hours a week might be helpful
, although more seems to be better.
Exactly how physical activity might reduce breast cancer risk isn’t
clear, but it may be due to its effects on body weight, inflammation,
hormones, and energy balance.
The American Cancer Society recommends
that adults get at least 150 minutes of moderate intensity or 75
minutes of vigorous intensity activity each week (or a combination of
these), preferably spread throughout the week.
Not having children
Women who have not had children or who had their first child after
age 30 have a slightly higher breast cancer risk overall. Having many
pregnancies and becoming pregnant at an early age reduces breast cancer
risk. Still, the effect of pregnancy seems to be different for different
types of breast cancer. For a certain type of breast cancer known as
triple-negative, pregnancy seems to increase risk.
Not breastfeeding
Some studies suggest that breastfeeding may slightly lower breast
cancer risk, especially if it’s continued for 1½ to 2 years.
But this has been hard to study, especially in countries like the
United States, where breastfeeding for this long is uncommon.
The explanation for this possible effect may be that breastfeeding
reduces a woman’s total number of lifetime menstrual cycles (the same as
starting menstrual periods at a later age or going through early
menopause).
Birth control
Some birth control methods use hormones, which might increase breast cancer risk.
Oral contraceptives: Most studies have found that
women using oral contraceptives (birth control pills) have a slightly
higher risk of breast cancer than women who have never used them. Once
the pills are stopped, this risk seems to go back to normal over time.
Women who stopped using oral contraceptives more than 10 years ago do
not appear to have any increased breast cancer risk.
Birth control shot:
Depo-Provera
is an injectable form of progesterone that’s given once every 3 months
for birth control. Some studies have found that women currently using
birth-control shots seem to have an increase in breast cancer risk,
but it appears that there is no increased risk in women 5 years
after they stop getting the shots.
Birth control implants, intrauterine devices (IUDs), skin patches, vaginal rings:
These forms of birth control also use hormones, which in theory could
fuel breast cancer growth. Some studies have shown a link between use of
hormone-releasing IUDs and breast cancer risk,
but few studies have looked at the use of birth control implants,
patches, and rings and breast cancer risk.
When thinking about using hormonal birth control, women should
discuss their other risk factors for breast cancer with their health
care provider.
Hormone therapy after menopause
Hormone therapy
with estrogen (often combined with progesterone) has been used for many
years to help relieve symptoms of menopause and help prevent
osteoporosis (thinning of the bones). This treatment goes by many names,
such as
post-menopausal hormone therapy (PHT),
hormone replacement therapy (HRT), and
menopausal hormone therapy (MHT).
There are 2 main types of hormone therapy. For women who still have
a uterus (womb), doctors generally prescribe estrogen and progesterone
(known as
combined hormone therapy or HT). Progesterone is needed because estrogen alone can increase the risk of cancer of the uterus. For women who’ve had a hysterectomy (who no longer have a uterus), estrogen alone can be used. This is known as
estrogen replacement therapy (ERT) or just
estrogen therapy (ET).
Combined hormone therapy (HT): Use of combined
hormone therapy after menopause increases the risk of breast cancer. It
may also increase the chances of dying from breast cancer. This increase
in risk can be seen with as little as 2 years of use. Combined HT also
increases the likelihood that the cancer may be found at a more advanced
stage.
The increased risk from combined HT appears to apply only to
current and recent users. A woman’s breast cancer risk seems to return
to that of the general population within 5 years of stopping treatment.
Bioidentical hormone therapy: The word
bioidentical
is sometimes used to describe versions of estrogen and progesterone
with the same chemical structure as those found naturally in people. The
use of these hormones has been marketed as a safe way to treat the
symptoms of menopause. But because there aren’t many studies comparing
“bioidentical” or “natural” hormones to synthetic versions of hormones,
there’s no proof that they’re safer or more effective. More studies are
needed to know for sure. The use of these bioidentical hormones should
be considered to have the same health risks as any other type of hormone
therapy.
Estrogen therapy (ET): The use of estrogen alone
after menopause does not seem to increase the risk of breast cancer
much, if at all. But when used long term (for more than 15 years), ET
has been found to increase the risk of ovarian and breast cancer in some
studies.
At this time there aren't many strong reasons to use
post-menopausal hormone therapy (either combined HT or ET), other than
possibly for the short-term relief of menopausal symptoms. Along with
the increased risk of breast cancer, combined HT also appears to
increase the risk of heart disease, blood clots, and strokes. It does
lower the risk of colorectal cancer and osteoporosis, but this must be
weighed against the possible harms, especially since there are other
ways to prevent and treat osteoporosis, and screening can sometimes prevent colon cancer. ET does not seem to increase breast cancer risk, but it does increase the risk of stroke.
The decision to use HT should be made by a woman and her doctor
after weighing the possible risks and benefits (including the severity
of her menopausal symptoms), and considering her other risk factors for
heart disease, breast cancer, and osteoporosis. If they decide she
should try HT for symptoms of menopause, it’s usually best to use it at
the lowest dose that works for her and for as short a time as possible.
Breast implants
Silicone breast implants can cause scar tissue to form in the
breast. Implants make breast tissue harder to see on standard
mammograms, but additional x-ray pictures called
implant displacement views can be used to examine the breast tissue more completely.
Certain types of breast implants can be linked to a rare type of cancer called anaplastic large cell lymphoma (ALCL).
It' is sometimes referred to as breast implant-associated anaplastic
large cell lymphoma (BIA-ALCL). This lymphoma appears to happen more
often in implants with textured (rough) surfaces rather than smooth
surfaces. If ALCL does show up after an implant, it can show up as a
lump, a collection of fluid near the implant, pain, swelling or
asymmetry (uneven breasts). It usually responds well to treatment.